Overview
Dr. Sarah Owen evaluates the safety of a wide range of chemicals as part of FDA submissions. Sarah brings more than 12 years of experience in public health protection and over 20 years of toxicology experience. Sarah is highly knowledgeable on human health risk assessment and toxicology testing, and is certified as a Diplomate of the American Board of Toxicology (DABT).
Prior to joining Steptoe, Sarah served as the State Toxicologist for the Vermont Department of Health, where she provided expert technical guidance on statewide environmental toxicology issues. She interpreted technical and complex data to evaluate environmental hazards and their potential impacts to public health. Sarah holds an Instructor position at the University of Vermont's Larner College of Medicine, Public Health Program.
Throughout her career, Sarah has overseen the development of risk assessment methods to assess chemicals in air, water, soil, and other media. This includes research into the toxicity of the chemical and consideration of exposure parameters, resulting in publication of hundreds of guidance values for these chemicals.
- Sarah Owen, Ph.D. is a Toxicology Specialist and does not provide legal advice.
- Ph.D., University of California, Berkeley, 2008, Molecular Toxicology
- B.S., Vanderbilt University, 1999, Molecular Biology
Events
Seminars & Events
Complimentary Food Contact Conference
April 29, 2025 - April 30, 2025
Speakers: Joan Baughan, Daniel C. Rubenstein, Joseph Dages, Kimberly Cassidy, Ph.D., Jessica Cooper, Ph.D., Patricia Kinne, Sarah Owen, Ph.D., DABT, Surya Kundu, Melanie A. Ayerh, Anthony G. Hopp, Michael Boucher, Eléonore Mullier, Tom Gillett
Noteworthy
Prior Publications
- Risk assessment, risk management, and regulation of halogenated organic chemicals: current practice and future directions. Carlson L, Kramel N, Lehmann D, Thomas K, Owen S, Maddaloni M, Ginsberg G, Poulsen M, Rajan P, Kapraun D, Foster S, Lehmann G. Advances in Neurotoxicology. (2023). Advances in Neurotoxicology Volume 10, 399- 443.
- Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model. Kajitani GS, Brace L, Trevino-Villarreal JH, Trocha K, MacArthur MR, Vose S, Vargas D, Bronson R, MItchell SJ, Menck CFM, Mitchell JR. Aging. (2021). Oct 10;13(19):22710-22731.
- Public health assessment of and response to perfluorooctanoic acid in drinking water, Bennington, Vermont. Prinzing L, Moore B, Grass D, Vose S, Voigt J, Chen H, Cragin L. Journal of Environmental Health. (2020) April 82:8, 9-15.
- Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma. Strobel T, Madlener S, Tuna S, Vose S, Lagerwehi T, Wurdinger T, Vierlinger K, Wohrer A, Price BD, Demple B, Saydam O, Saydem N. Scientific Reports. (2017) August 27 (7):9674.
- Increased oxidative phosphorylation in response to acute and chronic DNA damage. Brace L, Vose SC, Stanya K, Gathungu RM, Marur VR, Longchamp A, Trevino-Villarreal H, Mejia P, Vargas D, Inouye K, Bronson RT, Lee C-H, Neilan E, Kristal BS, Mitchell JR. Aging and Mechanisms of Disease. (2016) Oct 13 (2):16022.
- Short-term Preoperative Dietary Restriction Is Neuroprotective in a Rat Focal Stroke Model. Varendi K, Airavaara M, Anttila J, Vose S, Planken A, Saarma M, Mitchell JR, Andressoo JO. PLoS One. (2014) Apr 4;9(4)
- Lifespan extension by dietary intervention in a mouse model of Cockayne syndrome uncouples early postnatal development from segmental progeria. Brace LE, Vose SC, Vargas DF, Zhao S, Wang XP, Mitchell JR. Aging Cell. (2013) Dec;12(6):1144-7
- Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance. Madlener S, Ströbel T, Vose S, Saydam O, Price BD, Demple B, Saydam N. Proc Natl Acad Sci U S A. (2013) Oct 29;110(44):17844-9.
- Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice. Peng, W, Robertson, LT, Gallinetti, J, Mejia, P, Vose, S, Charlip, A, Chu, T, Mitchell, JR. Sci Transl Med. (2012) Jan 25,118.
- Relationship Between DNA Damage and Energy Metabolism: Evidence from DNA Repair Deficiency Syndromes, DNA Repair and Human Health, Sonya Vengrova (Ed.). Vose, SC and Mitchell, JR. ISBN: 978-953-307-612-6, InTech, 2011.
- Cellular function of neuropathy target esterase in lysophosphatidylcholine action. Vose, SC, Fujioka, K, Gulevich, AG, Lin, AY, Holland, NT, Casida, JE. Toxicol Appl Pharm (2008), 232, 376- 383.
- Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids. Casida JE, Nomura DK, Vose SC. Chem Biol Interact (2008), 175, 355- 364.
- Lysophosphatidylcholine hydrolases of human erythrocytes, lymphocytes and brain: sensitive targets of conserved specificity for organophosphorus delayed neurotoxicants. Vose SC, Holland NT, Eskenazi B, Casida JE. Toxicol Appl Pharm (2007), 224, 98- 104.
- Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates. Quistad BG, Fisher KJ, Owen SC, Klintenberg R, Casida JE. Toxicol Appl Pharm (2005) 205, 149-156.
Previous Employment
- State Toxicologist, Vermont Department of Health (2012- 2024)
- Instructor, University of Vermont Larner College of Medicine, Public Health Program (2016 – present)
- Postdoctoral Research Fellow, Harvard School of Public Health (2008-2012)
Professional Affiliations
- Society of Toxicology (2003- present)